StoneCLR

Ingredients

Phyllanthus Niruri (chanca piedra) - Phyllanthus niruri or chanca piedra is an herb that grows widely in coastal areas of India and tropical areas of South America. The extract has been used for hundreds of years to support gallbladder function and other urinary disorders. Chanca piedra also provides antioxidants, and muscle-relaxing agents, and immune-enhancing compounds to help overall health.* (Reference: Narendra, K., Swathi, J., Sowjanya, M., & Satya, A.K. (2012). Phyllanthus niruri: A Review on its Ethno Botanical, Phytochemical and Pharmacological Profile. Journal of Pharmacy Research 5(9),4681-4691. Reference 2: Boim, M., Heilber, I., & Schor, N. (2010). Phyllanthus niruri as a Promising Alternative Treatment for Nephrolithiasis. International braz j urol: official journal of the Brazilian Society of Urology 36(6):657-64.)

Parsley (Root) - Parsley is full of nutrients like vitamins A, K, and C. It is used to support kidney function but also to enhance the gallbladder. Parsley has also shown to help the urinary tract's role by decreasing calcium and protein excretion in the urine.* (Reference: Al-Yousofy, F., Gumaih, H., Ibrahim, H., & Alasbahy, A. (2017). Parsley! Mechanism as antiurolithiasis remedy. Am J Clin Exp Urol. 5(3): 55–62. Reference 2: Azab, A.E., Albasha, M.O., & Elsayed, A.S.I. (2017). Prevention of Nephropathy by Some Natural Sources of Antioxidants. Yangtze Medicine, 2017, 1, 235-266.)

Marshmallow (Root) - Marshmallow root extract (Althaea officinalis) has shown in studies to support the gallbladder and liver functions, assist digestion, stimulate heart health, and keep the lungs healthy. Marshmallow root is rich in antioxidants and immune-enhancing compounds that may help soothe the pain caused by inflammation in the gallbladder. It is also a soothing and mucilaginous herbal diuretic as well.* (Reference: Al-Snafi, A.E. (2013). The Pharmaceutical importance of Althaea officinalis and Althaea rosea: A review. International Journal of PharmTech Research 5(3):1378-1385 Reference 2: Clarebrough, E., Guest, G., & Stupart, D.A. (2015). Eating marshmallows reduces ileostomy output: A randomised crossover trial. Colorectal Disease 17(12).)

Turmeric (Root) Ext. 95% - Turmeric root extract contains curcumin, the primary dietary source of his herb. Curcumin is a potent antioxidant that supports the metabolic and nutritional alterations caused by gallbladder problems. Studies have shown that turmeric (curcumin) may stimulate bile formation to relieve the gallbladder emptying.* (Reference: Alvarenga, L.A., Leal, V.O., Borges, N., Silva de Aguilar, A., Irvin, G.F., Stenvinkel, P., Lindholm, B., & Mafra, D. (2018). Curcumin - A promising nutritional strategy for chronic kidney disease patients. Journal of Functional Foods 40:715-721. Reference 2: Rasyid, A., Rahman, A., Jaalam, K., & Lelo, A. (2002).  Effect of different curcumin dosages on human gall bladder. Asia Pacific Journal of Clinical Nutrition 11(4):314-8.)

Ginger (Root) - Ginger root has been recognized to have potent antioxidant properties, which are helpful to prevent oxidative stress in the gallbladder. Ginger can support the conversion of cholesterol into bile acids, which support the formation of gallstones. Ginger contains Vitamin C, magnesium, and other minerals needed to support the immune system.* (Reference: Seddik, A.A. (2016). The Effect of Turmeric and Ginger on Oxidative Modulation in end stage renal disease (ESRD) Patients. International Journal of Advanced Research (2015). Volume 3, Issue 11, 657-670. Reference 2: Chuah, S.K., Wu, K.L, & Tai, W.C. (2011). The Effects of Ginger on Gallbladder Motility in Healthy Male Humans. Journal of Neurogastroenterology and Motility 17(4):411-5)

Gravel (Root) - Gravel root extract is used to support the cleansing and detoxification of the liver, gallbladder, and urinary tract. Cleansing the gallbladder is essential to prevent gallstone formation. Gravel root provides positive health benefits to the bladder, prostate, and urinary tract health. It gently promotes healthy urine flow and soothes the delicate genito-urinary tissues.* (Reference: Habtemariam, S. (2001). Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): Further biological activities and constituents. Phytotherapy Research 15(8):687-90. Reference 2: Alok, S., Jain, S.K., Verma, A., Kumar, M., & Sabharwal, M. (2013). Pathophysiology of kidney, gallbladder and urinary stones treatment with herbal and allopathic medicine: A review. Asian Pac J Trop Dis. 3(6): 496–504.)

Lemon Balm (Leaf) - Lemon balm is commonly used in traditional medicine to support the gallbladder, liver, and gastrointestinal area. Lemon balm is part of the mint family. It has been used for thousands of years as a calming herb and an excellent natural detoxifier. It is an essential herb to alleviate the symptoms caused by gallbladder problems.* (Reference: Rezaei, M., Zamani, S., Ghasemi, A., Rahimi, A., Nabi, N., Changizi-Ashtiyani, S., & Ramezani, Z.A. (2015). The Effects of hydroalcoholic extract of Melissa officinalis L. on the level of renal function and liver enzymes in diabetic. Iranian Journal of Endocrinology and Metabolism. Vol 17 No. 5. Reference 2: Hosseini, S.M.R., Razmgah, G.R.G., Nematy, M., Esmaily, H., Yousefi, M., Kamalinejad, M., & Mosavat, S.H. (2018). Efficacy of Black Seed (Nigella sativa) and Lemon Balm (Melissa officinalis) on Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Clinical Trial. Iranian Red Crescent Medical Journal In Press(In Press).

Dandelion (Root) - Dandelion root is a powerful antioxidant source, which may provide support for overall healthy gallbladder and liver function. It has also been shown to support the urinary tract and the detoxification process of the bile duct. Dandelion root may also stimulate bile production in the gallbladder.* (Reference: Clare, B.A., Conroy, R.S., & Spelman, K. (2009). The Diuretic Effect in Human Subjects of an Extract of Taraxacum officinale Folium over a Single Day. J Altern Complement Med. 15(8): 929–934. Reference 2: Mohaddese, M., & Mahboubi, M. (2020). Hepatoprotection by dandelion ( Taraxacum officinale ) and mechanisms. Asian Pacific Journal of Tropical Biomedicine 10(1):1.)

Licorice (Root) - Licorice root has a long history of use, from the Egyptian to the Chinese, and even Indian cultures. It was traditionally used to support gallbladder, liver, and kidney conditions. The positive health benefits of licorice include immune-enhancing, and it may provide a calming effect caused by abdominal inflammation.* (Reference: Kao, T.C., Wu, C.H., & Yen, G.C. (2013). Bioactivity and potential health benefits of licorice. Journal of Agricultural and Food Chemistry 62(3). Reference 2: Njeze, G.E. (2013). Gallstones. Niger J Surg. 2013 Jul-Dec; 19(2): 49–55.)